Vitamin D, tryptophan and omega-3 to boost brain serotonin during pregnancy and beyond
This new study, Vitamin D hormone regulates serotonin synthesis. Part 1: relevance for autism (2013) by Dr. Ames and Rhonda Patrick demonstrates the impact of low vitamin D status on social behavior associated with autism spectrum disorders (ASD). The hormones serotonin, oxytocin, and vasopressin are all activated by vitamin D (which itself is a hormone).
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Vitamin D activates the enzyme TPH2 (tryptophan hydroxylase 2) that converts tryptophan to serotonin – the calming neurotransmitter in the brain. Vitamin D inhibits TPH1, which reduces serotonin in the gut and elsewhere, thus reducing inflammation.
